Recombinant Full Length Human HPN Protein

• Cat.No.: HPN-240HF
• Product Overview: Recombinant full length Human Hepsin with a N terminal proprietary tag. Predicted MW 67.69kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 378 amino acids
• Description: This gene encodes a type II transmembrane serine protease. The encoded protein has an extracellular region that consists of two domains, a catalytic serine protease domain and a non-catalytic scavenger receptor cysteine-rich domain. This protein may be involved in diverse cellular functions including blood coagulation, maintenance of cell morphology and the growth and progression of certain cancers, particularly prostate cancer. Alternative splicing results in multiple transcript variants.
• Form: Liquid
• Molecular Mass: 67.690kDa inclusive of tags
• AA Sequence: VAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSS RSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFC VDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLP VDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVL TAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVY HGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISN DVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFAC EDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREW IFQAIKTHSEASGMVTQL
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: HPN hepsin [ Homo sapiens ]
• Official Symbol: HPN
• Synonyms: HPN; hepsin; serine protease hepsin; TMPRSS1; transmembrane protease; serine 1
• Gene ID: 3249
• mRNA Refseq: NM_002151
• Protein Refseq: NP_002142
• MIM: 142440
• UniProt ID: P05981