Recombinant Full Length Human GSN Protein

Cat.No. : GSN-210HF
Product Overview : Recombinant full length Human Gelsolin with an N terminal proprietary tag; Predicted MWt 112.09 kDa.
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Species : Human
Source : In Vitro Cell Free System
Protein Length : 782 amino acids
Description : The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Form : Liquid
Molecular Mass : 112.090kDa inclusive of tags
AA Sequence : MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAP QGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVP VPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNEC SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRA TEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA TQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENP FAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMD DDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNY RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAP ASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPS AAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFV IEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEK TEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF LGWDDDYWSVDPLDRAMAELAA
Purity : Proprietary Purification
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
Storage Buffer : pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.
Gene Name GSN gelsolin [ Homo sapiens ]
Official Symbol GSN
Synonyms GSN; gelsolin; gelsolin (amyloidosis, Finnish type); amyloidosis; Finnish type; DKFZp313L0718
Gene ID 2934
mRNA Refseq NM_000177
Protein Refseq NP_000168
MIM 137350
UniProt ID P06396

Not For Human Consumption!

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