Description :	This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Source :	In Vitro Cell Free System
Species :	Human
Form :	Liquid
Molecular Mass :	72.930kDa inclusive of tags
Protein length :	429 amino acids
AA Sequence :	MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTP TMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEG WKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQL ANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFA DWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVY SCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIK SILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQ VTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAIN QDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIG GPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWT SRLRSHINPTGTVLLQLENTMQMSLKDLL
Purity :	Proprietary Purification
Storage :	Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
Storage Buffer :	pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Name	GLA galactosidase, alpha [ Homo sapiens ]
Official Symbol	GLA
Synonyms	GLA; galactosidase, alpha; alpha-galactosidase A; GALA
Gene ID	2717
mRNA Refseq	NM_000169
Protein Refseq	NP_000160
MIM	300644
UniProt ID	P06280

COA

Required fields are marked with *

Required fields are marked with *

Overall Rating *

Cat NO.

Review

Your Name

Phone Number

E-mail Address

Cat.No. :	GLA-194HF
Product Overview :	Recombinant full length Human Galactosidase alpha with a N terminal proprietary tag; predicted MWt 72.93 kDa inclusive of tag. AAH02689

Recombinant Full Length Human GLA Protein