Recombinant Full Length Human FUS Protein, N-His-tagged

• Cat.No.: FUS-12HFL
• Product Overview: Recombinant Full Length Human FUS Protein, fused to His-tag at N-terminus, was expressed in HEK293T.

Specification

• Description: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid
• Molecular Mass: 60 kDa
• Protein length: Ala2-Tyr526
• Purity: >95%
• Applications: Functional Assay, Protein-protein Interaction, Post-translational Modifications, ELISA, EIA, Western Blotting, Dot Blotting, Immunoprecipitation, Protein Array, etc.
• Storage: Upon arrival, the protein may be stored for 2 weeks at 4 centigrade. For long term storage, it is recommended to store at -20 centigrade or -80 centigrade in appropriate aliquots. Avoid repeated freeze-thaw cycles.
• Concentration: Lot specific (see the label on the vial), determined by Bradford protein assay.
• Storage Buffer: Filtered solution in 15 mM Na2HPO4 (pH 7.5), 5 mM NaH2PO4, 0.5 M NaCl, 40 mM imidazole, 6 M urea.
• Shipping: Ice packs
• Related Research Areas: Cancer

Gene Information

• Gene Name: FUS FUS RNA binding protein [ Homo sapiens (human) ]
• Official Symbol: FUS
• Synonyms: TLS; ALS6; ETM4; FUS1; POMP75; altFUS; HNRNPP2
• Gene ID: 2521
• mRNA Refseq: NM_004960.4
• Protein Refseq: NP_004951.1
• MIM: 137070
• UniProt ID: P35637