Recombinant Full Length Human FBXO42 Protein, GST-tagged

• Cat.No.: FBXO42-4678HF
• Product Overview: Human FBXO42 full-length ORF ( AAH43410.1, 1 a.a. - 716 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 104.2 kDa
• Protein length: 716 amino acids
• AA Sequence: MASSSDSEDDSFMAVDQEETVLEGT MDQDEEPHPVLEAEETRHNRSMSEL PEEVLEYILSFLSPYQEHKTAALVC KQWYRLIKGVAHQCYHGFMKAVQEG NIQWESRTYPYPGTPITQRFSHSAC YYDANQSMYVFGGCTQSSCNAAFND LWRLDLNSKEWIRPLASGSYPSPKA GATLVVYKDLLVLFGGWTRPSPYPL HQPERFFDEIHTYSPSKNWWNCIVT THGPPPMAGHSSCVIDDKMIVFGGS LGSRQMSNDVWVLDLEQWAWSKPNI SGPSPHPRGGQSQIVIDDATILILG GCGGPNALFKDAWLLHMHSGPWAWQ PLKVENEEHGAPELWCHPACRVGQC VVVFSQAPSGRAPLSPSLNSRPSPI SATPPALVPETREYRSQSPVRSMDE APCVNGRWGTLRPRAQRQTPSGSRE GSLSPARGDGSPILNGGSLSPGTAA VGGSLDSPVQAISPSTPSAPEGYDL KIGLSLAPRRGSLPDQKDLRLGSID LNWDLKPASSSNPMDGMDNRTVGGS MRHPPEQTNGVHTPPHVASALAGAV SPGALRRSLEAIKAMSSKGPSASAA LSPPLGSSPGSPGSQSLSSGETVPI PRPGPAQGDGHSLPPIARRLGHHPP QSLNVGKPLYQSMNCKPMQMYVLDI KDTKEKGRVKWKVFNSSSVVGPPET SLHTVVQGRGELIIFGGLMDKKQNV KYYPKTNALYFVRAKR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXO42 F-box protein 42 [ Homo sapiens ]
• Official Symbol: FBXO42
• Synonyms: FBXO42; F-box protein 42; F-box only protein 42; Fbx42; KIAA1332; just one F-box and Kelch domain-containing protein; JFK
• Gene ID: 54455
• mRNA Refseq: NM_018994
• Protein Refseq: NP_061867
• MIM: 609109
• UniProt ID: Q6P3S6