Recombinant Full Length Human FBLN1 Protein

• Cat.No.: FBLN1-166HF
• Product Overview: Recombinant full length Human Fibulin 1 with N terminal proprietary tag; Predicted MWt 101.2 kDa inclusive of tag.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 683 amino acids
• Description: Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3 end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
• Form: Liquid
• Molecular Mass: 101.200kDa inclusive of tags
• AA Sequence: MERAAPSRRVPLQLLLLGGLALLAAGVDADVLLEACCADG HRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELHCAT GISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ AQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQE TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCS CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ NTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDV NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG SNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY RRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQAP AVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSG VVALTKPVPEPRDLLLTVKMDLSRHGTVSSFVAKLFIFVS AEL
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: FBLN1 fibulin 1 [ Homo sapiens ]
• Official Symbol: FBLN1
• Synonyms: FBLN1; fibulin 1; fibulin-1; FBLN
• Gene ID: 2192
• mRNA Refseq: NM_001996
• Protein Refseq: NP_001987
• MIM: 135820
• UniProt ID: P23142