Recombinant Full Length Human FASN protein, Flag-tagged

• Cat.No.: FASN-4433HFL
• Product Overview: Recombinant Full Length Human FASN protein, fused with C-terminal Flag tag, was expressed in mamanlian cells.

Specification

• Source: Mamanlian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 273.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Shipping: The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Gene Information

• Gene Name: FASN fatty acid synthase [ Homo sapiens ]
• Official Symbol: FASN
• Synonyms: FASN; fatty acid synthase; FAS; SDR27X1; short chain dehydrogenase/reductase family 27X; member 1; short chain dehydrogenase/reductase family 27X, member 1; OA-519; MGC14367; MGC15706
• Gene ID: 2194
• mRNA Refseq: NM_004104
• Protein Refseq: NP_004095
• MIM: 600212
• UniProt ID: P49327

Reviews

12/13/2022

Its high quality and purity ensure accurate and reliable results.

07/26/2017

With the manufacturer's unwavering dedication to delivering quality products and unparalleled technical support, I am confident in their ability to help me overcome any challenges and propel my research forward.

06/20/2017

The FASN protein exhibits several valuable attributes that make it an excellent choice for my trials.

Q&As

Are there any ongoing clinical trials targeting FASN for therapeutic purposes?

Yes, several clinical trials are investigating FASN inhibitors as potential treatments for cancer and metabolic disorders.

How does FASN relate to insulin resistance and diabetes?

FASN has been associated with insulin resistance, and its inhibition is being investigated as a potential avenue for treating insulin resistance and type 2 diabetes.

Can FASN inhibitors be used in combination with other cancer therapies?

Combination therapies involving FASN inhibitors and other anticancer drugs are being explored to enhance treatment efficacy and reduce potential resistance.

How does FASN influence the development and progression of obesity?

FASN is involved in the synthesis of fatty acids, and its dysregulation can contribute to excessive fat accumulation, potentially leading to obesity.

Does FASN play a role in neurodegenerative diseases?

Emerging research suggests a potential link between FASN and neurodegenerative diseases, but more studies are needed to fully understand this connection.