Recombinant Full Length Human FARS2 Protein, GST-tagged

• Cat.No.: FARS2-4758HF
• Product Overview: Human FARS2 full-length ORF ( NP_006558.1, 1 a.a. - 451 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 78.8 kDa
• Protein length: 451 amino acids
• AA Sequence: MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKYPAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRHMERTLSQREVRHIHQALQEAAVQLLGVEGRF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial [ Homo sapiens ]
• Official Symbol: FARS2
• Synonyms: FARS2; phenylalanyl-tRNA synthetase 2, mitochondrial; FARS1, phenylalanine tRNA synthetase 1 (mitochondrial); phenylalanine--tRNA ligase, mitochondrial; dJ236A3.1; phenylalanine tRNA ligase 2; mitochondrial; phenylalanine translase; dJ236A3.1 (phenylalanine-tRNA synthetase); phenylalanine tRNA ligase 2, mitochondrial; phenylalanyl-tRNA synthetase, mitochondrial; phenylalanine-tRNA synthetase 1 (mitochondrial); phenylalanine-tRNA synthetase 2 (mitochondrial); dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase)); FARS1; PheRS; HSPC320; dJ520B18.2
• Gene ID: 10667
• mRNA Refseq: NM_006567
• Protein Refseq: NP_006558
• MIM: 611592
• UniProt ID: O95363