Recombinant Full Length Human F2RL2 Protein

• Cat.No.: F2RL2-4498HF
• Product Overview: Human F2RL2 full-length ORF (NP_004092.1) recombinant protein without tag.

Specification

• Description: This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 42.5 kDa
• Protein length: 352 amino acids
• AA Sequence: MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH 8.0 containing 2% glycerol.

Gene Information

• Gene Name: F2RL2 coagulation factor II (thrombin) receptor-like 2 [ Homo sapiens ]
• Official Symbol: F2RL2
• Synonyms: F2RL2; coagulation factor II (thrombin) receptor-like 2; proteinase-activated receptor 3; PAR3; proteinase activated receptor 3; thrombin receptor-like 2; protease-activated receptor 3; proteinase-activated receptor-3; Coagulation factor II receptor-like 2 (protease-actovated receptor 3); PAR-3; FLJ51933
• Gene ID: 2151
• mRNA Refseq: NM_001256566
• Protein Refseq: NP_001243495
• MIM: 601919
• UniProt ID: O00254