F2RL2
-
Official Full Name
coagulation factor II (thrombin) receptor-like 2 -
Overview
This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012] -
Synonyms
F2RL2;coagulation factor II (thrombin) receptor-like 2;PAR3;PAR-3;proteinase-activated receptor 3;thrombin receptor-like 2;protease-activated receptor 3;proteinase-activated receptor-3;Coagulation factor II receptor-like 2 (protease-actovated receptor 3)
Recombinant Proteins
- Rat
- Human
- Mouse
- Mus musculus
- Bovine
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- His
- Non
- Avi
- Fc
Involved Pathway
F2RL2 involved in several pathways and played different roles in them. We selected most pathways F2RL2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with F2RL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | P2RY2,TAAR12F,GPR50,GRIK1,F2RL1,S1PR5,SCTR,PRL2,DRD7,HTR2B |
Protein Function
F2RL2 has several biochemical functions, for example, G-protein coupled receptor activity,signal transducer activity,thrombin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by F2RL2 itself. We selected most functions F2RL2 had, and list some proteins which have the same functions with F2RL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| signal transducer activity | CTNNB1,GNAI2B,NPFFR1L3,TMTOPS2A,MAGI2,STAT2,MC5RA,GPR152,MAPKAPK2,GPR82 |
| G-protein coupled receptor activity | GHSRA,MTNR1B,OR8A1,GNRHR2,RXFP3.2B,LPAR5A,GPR56,OLFR688,F2R,GPRC5C |
| thrombin receptor activity | F2RL1.1,F2R,F2RL1,F2RL1.2,GP1BA |
Interacting Protein
F2RL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with F2RL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of F2RL2.
Smad7;Smad1;Smad4;Smad2;SMAD3
Resources
Related Services
Related Products
References
