Recombinant Full Length Human EXTL2 Protein, Flag-tagged

• Cat.No.: EXTL2-4451HF
• Product Overview: Recombinant protein of human exostoses (multiple)-like 2 (EXTL2), transcript variant 1 with C-terminal DDK/His tag, expressed in human cells.

Specification

• Description: Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
• Source: HEK293T
• Species: Human
• Tag: C-DDK/His
• Protein length: Full length
• Molecular Mass: 37.3 kDa
• AA Sequence: MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGKSTMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTTDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMISQFGFPYANYKRKITRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: > 0.05 μg/μL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol

Gene Information

• Gene Name: EXTL2 exostosin like glycosyltransferase 2 [ Homo sapiens (human) ]
• Official Symbol: EXTL2
• Synonyms: EXTL2; exostosin like glycosyltransferase 2; EXTR2; exostosin-like 2; EXT-related protein 2; alpha-1,4-N-acetylhexosaminyltransferase EXTL2; alpha-GalNAcT EXTL2; exostoses (multiple)-like 2; glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; processed exostosin-like 2; EC 2.4.1.223
• Gene ID: 2135
• mRNA Refseq: NM_001439
• Protein Refseq: NP_001430
• MIM: 602411
• UniProt ID: Q9UBQ6