Recombinant Full Length Human ERVFRD-1 Protein, GST-tagged

• Cat.No.: ERVFRD-1-4694HF
• Product Overview: Human ERVFRD-1 full-length ORF ( AAH68585.1, 1 a.a. - 538 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 538 amino acids
• Description: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Jun 2012]
• Molecular Mass: 85.9 kDa
• AA Sequence: MGLLLLVLILTPSLAAYRHPDFPLLEKAQQLLQSTGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKGLMRPANSLLSTVKQDFPDIRQKPPIFGPIFTNINLMGIAPICVMAKRKNGTNVGTLPSTVCNVTFTVDSNQQTYQTYTHNQFRHQPRFPKPPNITFPQGTLLDKSSRFCQGRPSSCSTRNFWFRPADYNQCLQISNLSSTAEWVLLDQTRNSLFWENKTKGANQSQTPCVQVLAGMTIATSYLGISAVSEFFGTSLTPLFHFHISTCLKTQGAFYICGQSIHQCLPSNWTGTCTIGYVTPDIFIAPGNLSLPIPIYGNSPLPRVRRAIHFIPLLAGLGILAGTGTGIAGITKASLTYSQLSKEIANNIDTMAKALTTMQEQIDSLAAVVLQNRRGLDMLTAAQGGICLALDEKCCFWVNQSGKVQDNIRQLLNQASSLRERATQGWLNWEGTWKWFSWVLPLTGPLVSLLLLLLFGPCLLNLITQFVSSRLQAIKLQTNLSAGRHPRNIQESPF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ERVFRD-1 endogenous retrovirus group FRD, member 1 [ Homo sapiens ]
• Official Symbol: ERVFRD-1
• Synonyms: ERVFRD-1; endogenous retrovirus group FRD, member 1; HERV-FRD_6p24.1 provirus ancestral Env polyprotein; envFRD; ERVFRDE1; HERV FRD; HERV W/FRD; syncytin 2; envelope polyprotein; endogenous retrovirus group FRD member 1; HERV-FRD provirus ancestral Env polyprotein; UNQ6191; GLLL6191; HERV-FRD; HERV-W/FRD; FLJ41944; FLJ90611; MGC87585
• Gene ID: 405754
• mRNA Refseq: NM_207582
• Protein Refseq: NP_997465
• MIM: 610524
• UniProt ID: P60508