Recombinant Full Length Human ERAS Protein, C-Flag-tagged

• Cat.No.: ERAS-716HFL
• Product Overview: Recombinant Full Length Human ERAS Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 25.1 kDa
• AA Sequence: MELPTKPGTFDLGLATWSPSFQGET HRAQARRRDVGRQLPEYKAVVVGAS GVGKSALTIQLNHQCFVEDH DPTIQDSYWKELTLDSGDCILNVLD TAGQAIHRALRDQCLAVCDGVLGVF ALDDPSSLIQLQQIWATWGP HPAQPLVLVGNKCDLVTTAGDAHAA AAALAHSWGAHFVETSAKTRQGVEE AFSLLVHEIQRVQEAMAKEP
  MARSCREKTRHQKATCHCGCSVATR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: ERAS ES cell expressed Ras [ Homo sapiens (human) ]
• Official Symbol: ERAS
• Synonyms: HRAS2; HRASP
• Gene ID: 3266
• mRNA Refseq: NM_181532.3
• Protein Refseq: NP_853510.1
• MIM: 300437
• UniProt ID: Q7Z444