Recombinant Full Length Human ERAL1 Protein, GST-tagged

• Cat.No.: ERAL1-4355HF
• Product Overview: Human ERAL1 full-length ORF ( AAH19094, 1 a.a. - 437 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 73.81 kDa
• Protein length: 437 amino acids
• AA Sequence: MAAPSWRGARLVQSVLRVWQVGPHV ARERVIPFSSLLGFQRRCVSCVAGS AFSGPRLASASRSNGQGSALDHFLG FSQPDSSVTPCVPAVSMNRDEQDVL LVHHPDMPENSRVLRVVLLGAPNAG KSTLSNQLLGRKVFPVSRKVHTTRC QALGVITEKETQVILLDTPGIISPG KQKRHHLELSLLEDPWKSMESADLV VVLVDVSDKWTRNQLSPQLLRCLTK YSQIPSVLVMNKVDCLKQKSVLLEL TAALTEGVVNGKKLKMRQAFHSHPG THCPSPAVKDPNTQSVGNPQRIGWP HFKEIFMLSALSQEDVKTLKQYLLT QAQPGPWEYHSAVLTSQTPEEICAN IIREKLLEHLPQEVPYNVQQKTAVW EEGPGGELVIQQKLLVPKESYVKLL IGPKGHVISQIAQEAGHDLMDIFLC DVDIRLSVKLLK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ERAL1 Era G-protein-like 1 (E. coli) [ Homo sapiens ]
• Official Symbol: ERAL1
• Synonyms: ERAL1; Era G-protein-like 1 (E. coli); Era (E. coli G protein homolog) like 1; GTPase Era, mitochondrial; HERA B; CEGA; hERA; ERA-W; ERA-like protein 1; conserved ERA-like GTPase; GTP-binding protein era homolog; era (E. coli G-protein homolog)-like 1; GTPase, human homolog of E. coli essential cell cycle protein Era; ERA; H-ERA; ERAL1A; HERA-A; HERA-B
• Gene ID: 26284
• mRNA Refseq: NM_005702
• Protein Refseq: NP_005693
• MIM: 607435
• UniProt ID: O75616