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ERAL1

Official Full Name

Era G-protein-like 1 (E. coli)
Overview

ERAL1, a homologue of Era protein in Escherichia coli, is a member of conserved GTP-binding proteins with RNA-binding activity.
Synonyms

ERAL1; Era G-protein-like 1 (E. coli); ERA; H-ERA; ERAL1A; HERA-A; HERA-B; ERA2; Era (E. coli G-protein homolog)-like 1; Conserved ERA-like GTPas; OTTHUMP00000163515; CEGA; GTP-binding protein era homolog; ERA-W; GTPase Era, mitochondrial; GTPase, human homolog of E. coli essential cell cycle protein Era; ERA-like protein 1; hERA;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ERAL1-12512H	Recombinant Human ERAL1, GST-tagged	E.coli	GST	C-term-300a.a.	$319 / 25μg
Human	ERAL1-3438H	Recombinant Human ERAL1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ERAL1-6571HCL	Recombinant Human ERAL1 293 Cell Lysate	HEK293	Non		Inquiry
Human	ERAL1-4355HF	Recombinant Full Length Human ERAL1 Protein, GST-tagged	In Vitro Cell Free System	GST	437 amino acids	Inquiry
Mouse	ERAL1-5275M	Recombinant Mouse ERAL1 Protein	Mammalian Cell	His		Inquiry
Mouse	ERAL1-2839M	Recombinant Mouse ERAL1 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	ERAL1-2839M-B	Recombinant Mouse ERAL1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ERAL1-2131R	Recombinant Rat ERAL1 Protein	Mammalian Cell	His		Inquiry
Rat	ERAL1-1788R	Recombinant Rat ERAL1 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rat	ERAL1-1788R-B	Recombinant Rat ERAL1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ERAL1-7017Z	Recombinant Zebrafish ERAL1	Mammalian Cell	His		Inquiry
Chicken	ERAL1-5812C	Recombinant Chicken ERAL1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

ERAL1 involved in several pathways and played different roles in them. We selected most pathways ERAL1 participated on our site, such as Integrated Breast Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERAL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Integrated Breast Cancer Pathway	DAG1;JAKMIP1;ALKBH1;MYT1;ANXA1;PLK3;GDI1;GRN;C21orf7

ERAL1 has several biochemical functions, for example, GTP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERAL1 itself. We selected most functions ERAL1 had, and list some proteins which have the same functions with ERAL1. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	RAB6B;GFM1;RAB42A;EEF2A.2;IFT27;RAC3B;TUBAL3;RRAGCA;SPAG1
poly(A) RNA binding	TDRD9;SCAF4;MYBBP1A;SUPT6H;MRPS12;RBM12B2;PA2G4;DCD;RPGR
protein binding	DTD2;PYCARD;MOCS3;ECH1;NFE2L2;UBE2G2;C19orf57;CCDC42;MAP3K7IP3
rRNA binding	RPL23A;DIEXF;RPL8;RPS9;FASTKD2;RPS4Y2;RPF2;PTCD3;MTERFD2
ribosomal small subunit binding	NPM1;NME1;PTCD3;CPEB2;PIM1;MTIF3;ERAL1;DDX3X;DHX29

ERAL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERAL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERAL1.

CEP44; C1qbp; XRCC3; ICT1; Med22; CDC5L; ANKFY1; Mta2; L1RE1

Research Area

Janer, A; Antonicka, H; et al. An RMND1 Mutation Causes Encephalopathy Associated with Multiple Oxidative Phosphorylation Complex Deficiencies and a Mitochondrial Translation Defect. AMERICAN JOURNAL OF HUMAN GENETICS 91:737-743(2012).

Xie, XL; Le, L; et al. Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition. AUTOPHAGY 8:1071-1084(2012).