Recombinant Full Length Human EPB41 Protein

• Cat.No.: EPB41-157HF
• Product Overview: Recombinant full length Human EPB41 with N terminal proprietary tag, 105.27kDa.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 720 amino acids
• Description: The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Molecular Mass: 105.270kDa inclusive of tags
• AA Sequence: MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQ TAAEGDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLS RLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQE ELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKAS QKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPW NFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPC SFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDL HKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKI SYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQA SALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTS APAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED EPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQKKRERL DGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFME SVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGVSTLST
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: EPB41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) [ Homo sapiens ]
• Official Symbol: EPB41
• Synonyms: EPB41; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); EL1; protein 4.1; 4.1R
• Gene ID: 2035
• mRNA Refseq: NM_001166005
• Protein Refseq: NP_001159477
• MIM: 130500
• UniProt ID: P11171