Recombinant Full Length Human EIF2S1 Protein, GST-tagged
Cat.No. : | EIF2S1-4186HF |
Product Overview : | Human EIF2S1 full-length ORF ( AAH02513.1, 1 a.a. - 315 a.a.) recombinant protein with GST-tag at N-terminal. |
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Species : | Human |
Source : | In Vitro Cell Free System |
Tag : | GST |
Protein Length : | 315 amino acids |
Description : | The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010] |
Molecular Mass : | 60.39 kDa |
AA Sequence : | MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVDGDDDAEEMEAKAED |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name | EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa [ Homo sapiens ] |
Official Symbol | EIF2S1 |
Synonyms | EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; EIF2, eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ); eukaryotic translation initiation factor 2 subunit 1; EIF 2alpha; EIF2A; eIF-2-alpha; eukaryotic translation initiation factor 2 subunit alpha; EIF2; EIF-2; EIF-2A; EIF-2alpha; |
Gene ID | 1965 |
mRNA Refseq | NM_004094 |
Protein Refseq | NP_004085 |
MIM | 603907 |
UniProt ID | P05198 |
◆ Recombinant Proteins | ||
EIF2S1-3172H | Recombinant Human EIF2S1 Protein, GST-tagged | +Inquiry |
EIF2S1-820H | Recombinant Human EIF2S1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF2S1-371H | Recombinant Human EIF2S1 Protein, MYC/DDK-tagged | +Inquiry |
EIF2S1-1709R | Recombinant Rat EIF2S1 Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF2S1-1419R | Recombinant Rhesus monkey EIF2S1 Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
EIF2S1-542HCL | Recombinant Human EIF2S1 cell lysate | +Inquiry |
Not For Human Consumption!
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