Recombinant Full Length Human EIF2B5 Protein, GST-tagged

• Cat.No.: EIF2B5-4546HF
• Product Overview: Human EIF2B5 full-length ORF ( AAH13590.1, 1 a.a. - 721 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 106.8 kDa
• Protein length: 721 amino acids
• AA Sequence: MAAPVVAPPGVVVSRANKRSGAGPG GSGGGGARGAEEEPPPPLQAVLVAD SFDRRFFPISKDQPRVLLPLANVAL IDYTLEFLTATGVQETFVFCCWKAA QIKEHLLKSKWCRPTSLNVVRIITS ELYRSLGDVLRDVDAKALVRSDFLL VYGDVISNINITRALEEHRLRRKLE KNVSVMTMIFKESSPSHPTRCHEDN VVVAVDSTTNRVLHFQKTQGLRRFA FPLSLFQGSSDGVEVRYDLLDCHIS ICSPQVAQLFTDNFDYQTRDDFVRG LLVNEEILGNQIHMHVTAKEYGARV SNLHMYSAVCADVIRRWVYPLTPEA NFTDSTTQSCTHSRHNIYRGPEVSL GHGSILEENVLLGSGTVIGSNCFIT NSVIGPGCHIGDNVVLDQTYLWQGV RVAAGAQIHQSLLCDNAEVKERVTL KPRSVLTSQVVVGPNITLPEGSVIS LHPPDAEEDEDDGEFSDDSGADQEK DKVKMKGYNPAEVGAAGKGYLWKAA GMNMEEEEELQQNLWGLKINMEEES ESESEQSMDSEEPDSRGGSPQMDDI KVFQNEVLGTLQRGKEENISCDNLV LEINSLKYAYNVSLKEVMQVLSHVV LEFPLQQMDSPLDSSRYCALLLPLL KAWSPVFRNYIKRAADHLEALAAIE DFFLEHEALGISMAKVLMAFYQLEI LAEETILSWFSQRDTTDKGQQLRKN QQLQRFIQWLKEAEEESSEDD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa [ Homo sapiens ]
• Official Symbol: EIF2B5
• Synonyms: EIF2B5; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; eukaryotic translation initiation factor 2B, subunit 5 (epsilon, 82kD); translation initiation factor eIF-2B subunit epsilon; EIF 2B; EIF2Bepsilon; eIF-2B GDP-GTP exchange factor subunit epsilon; CLE; CACH; LVWM; EIF-2B
• Gene ID: 8893
• mRNA Refseq: NM_003907
• Protein Refseq: NP_003898
• MIM: 603945
• UniProt ID: Q13144