Recombinant Full Length Human EFS Protein, GST-tagged

• Cat.No.: EFS-4238HF
• Product Overview: Human EFS full-length ORF ( NP_115835.1, 1 a.a. - 468 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 75.4 kDa
• Protein length: 468 amino acids
• AA Sequence: MAIATSVYVVPPPARPCPTSGPPAG PCPPSPDLIYKIPRASGTQLAAPRD ALEVYDVPPTALRVPSSGPYDCPAS FSHPLTRVAPQPPGEDDAPYDVPLT PKPPAELEPDLEWEGGREPGPPIYA APSNLKRASALLNLYEAPEELLADG EGGGTDEGIYDVPLLGPEAPPSPEP PGALASHDQDTLAQLLARSPPPPHR PRLPSAESLSRRPLPALPVPEAPSP SPVPSPAPGRKGSIQDRPLPPPPPR LPGYGGPKVEGDPEGREMEDDPAGH HNEYEGIPMAEEYDYVHLKGMDKAQ GSRPPDQACTGDPELPERGMPAPQE ALSPGEPLVVSTGDLQLLYFYAGQC QSHYSALQAAVAALMSSTQANQPPR LFVPHSKRVVVAAHRLVFVGDTLGR LAASAPLRAQVRAAGTALGQALRAT VLAVKGAALGYPSSPAIQEMVQCVT ELAGQALQFTTLLTSLAP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EFS embryonal Fyn-associated substrate [ Homo sapiens ]
• Official Symbol: EFS
• Synonyms: EFS; embryonal Fyn-associated substrate; Cas scaffolding protein family member 3; CASS3; EFS1; EFS2; HEFS; SIN; signal transduction protein (SH3 containing); CAS3
• Gene ID: 10278
• mRNA Refseq: NM_005864
• Protein Refseq: NP_005855
• MIM: 609906
• UniProt ID: O43281