Recombinant Full Length Human DSCR3 Protein, GST-tagged

• Cat.No.: DSCR3-4196HF
• Product Overview: Human DSCR3 full-length ORF (BAG35585.1, 1 a.a. - 297 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 59.07 kDa
• Protein length: 297 amino acids
• AA Sequence: MGTALDIKIKRANKVYHAGEVLSGV VVISSKDSVQHQGVSLTMEGTVNLQ LSAKSVGVFEAFYNSVKPIQIINST IEMVKPGKFPSGKTEIPFEFPLHLK GNKVLYETYHGVFVNIQYTLRCDMK RSLLAKDLTKTCEFIVHSAPQKGKF TPSPVDFTITPETLQNVKERALLPK FLLRGHLNSTNCVITQPLTGELVVE SSEAAIRSVELQLVRVETCGCAEGY ARDATEIQNIQIADGDVCRGLSVPI YMVFPRLFTCPTLETTNFKVEFEVN IVVLLHPDHLITENFPLKLCRI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DSCR3 DSCR3 arrestin fold containing [ Homo sapiens (human) ]
• Official Symbol: DSCR3
• Synonyms: DSCR3; DSCR3 arrestin fold containing; DSCR3 Arrestin Fold Containing; Down Syndrome Critical Region Protein A; Down Syndrome Critical Region 3; DSCRA; DCRA; Down Syndrome Critical Region Protein 3; Down Syndrome Critical Region Gene 3; Down syndrome critical region protein 3; Down syndrome critical region 3; Down syndrome critical region gene 3; Down syndrome critical region protein A
• Gene ID: 10311
• mRNA Refseq: NM_001331018
• Protein Refseq: NP_001317947
• MIM: 605298
• UniProt ID: O14972