Recombinant Full Length Human DSCC1 Protein, GST-tagged

• Cat.No.: DSCC1-2797HF
• Product Overview: Human DCC1 full-length ORF ( AAH01316, 1 a.a. - 393 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 68.97 kDa
• Protein length: 393 amino acids
• AA Sequence: MKRTRDEVDATLQIAKLNAAELLPAVHCLGFGPGASGAAAGDFCLLELEPTLCQQLEDGHSLVIRGDKDEQAVLCSKDKTYDLKIADTSNMLLFIPGCKTPDQLKKEDSHCNIIHTEIFGFSNNYWELRRRRPKLKKLKKLLMENPYEGPDSQKEKDSNSSKYTTEDLLDQIQASEEEIMTQLQVLNACKIGGYWRILEFDYEMKLLNHVTQLVDSESWSFGKVPLNTCLQELGPLEPEEMIEHCLKCYGKKYVDEGEVYFELDADKICRAAARMLLQNAVKFNLAEFQEVWQQSVPEGMVTSLDQLKGLALVDRHSRPEIIFLLKVDDLPEDNQERFNSLFSLREKWTEEDIAPYIQDLCGEKQTIGALLTKYSRSSMQNGVKVYNSRRPIS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DSCC1 defective in sister chromatid cohesion 1 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DSCC1
• Synonyms: DSCC1; defective in sister chromatid cohesion 1 homolog (S. cerevisiae); sister chromatid cohesion protein DCC1; DCC1; defective in sister chromatid cohesion homolog 1 (S. cerevisiae); hDCC1; MGC5528; defective in sister chromatid cohesion protein 1 homolog
• Gene ID: 79075
• mRNA Refseq: NM_024094
• Protein Refseq: NP_076999
• MIM: 613203
• UniProt ID: Q9BVC3