Recombinant Full Length Human DNAJC21 Protein, GST-tagged

• Cat.No.: DNAJC21-4005HF
• Product Overview: Human DNAJC21 full-length ORF ( AAI41524.1, 1 a.a. - 576 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the precursor 45S ribosomal RNA and may be involved in early nuclear ribosomal RNA biogenesis and maturation of the 60S ribosomal subunit. Mutations in this gene result in Bone marrow failure syndrome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2017]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 89.76 kDa
• Protein length: 576 amino acids
• AA Sequence: MKCHYEALGVRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELESVLEEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLVEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDEAEDAELYDDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEENFSRPQIDENPLDDNSEEEMEDAPKQKLSKKQKKKKQKPAQDVPGKDSYLPAAHFQMAWGKKCVLGERRDGESEHKCAKMLLENRQNYDDNFNVNGPGEGVKVDPEDTNLNQDSAKELEDSPQENVSVTEIIKPCDDPKSEAKSVPKPKGKKTKDMKKPVRVPAEPQTMSVLISCTTCHSEFPSRNKLFDHLKATGHARAPSSSSLNSATSSQSKKEKRKNR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 [ Homo sapiens ]
• Official Symbol: DNAJC21
• Synonyms: DNAJC21; DnaJ (Hsp40) homolog, subfamily C, member 21; dnaJ homolog subfamily C member 21; DNAJA5; GS3; JJJ1; JJJ1 DnaJ domain protein homolog (S. cerevisiae); JJJ1 DnaJ domain protein homolog; dnaJ homolog subfamily A member 5; DnaJ homology subfamily A member 5
• Gene ID: 134218
• mRNA Refseq: NM_001012339
• Protein Refseq: NP_001012339
• MIM: 617048
• UniProt ID: Q5F1R6