Recombinant Full Length Human DNAJB4 Protein, GST-tagged
Cat.No. : | DNAJB4-3981HF |
Product Overview : | Human DNAJB4 full-length ORF ( AAH34721, 1 a.a. - 337 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 62.81 kDa |
Protein length : | 337 amino acids |
AA Sequence : | MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name | DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 [ Homo sapiens ] |
Official Symbol | DNAJB4 |
Synonyms | DNAJB4; DnaJ (Hsp40) homolog, subfamily B, member 4; dnaJ homolog subfamily B member 4; HLJ1; HSP40 homolog; heat shock protein 40 homolog; human liver DnaJ-like protein; DnaJ-like heat shock protein 40; heat shock 40 kDa protein 1 homolog; DjB4; DNAJW; |
Gene ID | 11080 |
mRNA Refseq | NM_007034 |
Protein Refseq | NP_008965 |
MIM | 611327 |
UniProt ID | Q9UDY4 |
Not For Human Consumption!
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