Recombinant Full Length Human DNAJB4 Protein, GST-tagged

Cat.No. : DNAJB4-3981HF
Product Overview : Human DNAJB4 full-length ORF ( AAH34721, 1 a.a. - 337 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 62.81 kDa
Protein length : 337 amino acids
AA Sequence : MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 [ Homo sapiens ]
Official Symbol DNAJB4
Synonyms DNAJB4; DnaJ (Hsp40) homolog, subfamily B, member 4; dnaJ homolog subfamily B member 4; HLJ1; HSP40 homolog; heat shock protein 40 homolog; human liver DnaJ-like protein; DnaJ-like heat shock protein 40; heat shock 40 kDa protein 1 homolog; DjB4; DNAJW;
Gene ID 11080
mRNA Refseq NM_007034
Protein Refseq NP_008965
MIM 611327
UniProt ID Q9UDY4

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