Recombinant Full Length Human DLG3 Protein, C-Flag-tagged

• Cat.No.: DLG3-1489HFL
• Product Overview: Recombinant Full Length Human DLG3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 90.1 kDa
• AA Sequence: MHKHQHCCKCPECYEVTRLAALRRL EPPGYGDWQVPDPYGPGGGNGASAG YGGYSSQTLPSQAGATPTPR TKAKLIPTGRDVGPVPPKPVPGKST PKLNGSGPSWWPECTCTNRDWYEQV NGSDGMFKYEEIVLERGNSG LGFSIAGGIDNPHVPDDPGIFITKI IPGGAAAMDGRLGVNDCVLRVNEVD VSEVVHSRAVEALKEAGPVV RLVVRRRQPPPETIMEVNLLKGPKG LGFSIAGGIGNQHIPGDNSIYITKI IEGGAAQKDGRLQIGDRLLA VNNTNLQDVRHEEAVASLKNTSDMV YLKVAKPGSLHLNDMYAPPDYASTF TALADNHISHNSSLGYLGAV ESKVSYPAPPQVPPTRYSPIPRHML AEEDFTREPRKIILHKGSTGLGFNI VGGEDGEGIFVSFILAGGPA DLSGELRRGDRILSVNGVNLRNATH EQAAAALKRAGQSVTIVAQYRPEEY SRFESKIHDLREQMMNSSMS SGSGSLRTSEKRSLYVRALFDYDRT RDSCLPSQGLSFSYGDILHVINASD DEWWQARLVTPHGESEQIGV IPSKKRVEKKERARLKTVKFHARTG MIESNRDFPGLSDDYYGAKNLKGQE DAILSYEPVTRQEIHYARPV IILGPMKDRVNDDLISEFPHKFGSC VPHTTRPRRDNEVDGQDYHFVVSRE QMEKDIQDNKFIEAGQFNDN LYGTSIQSVRAVAERGKHCILDVSG NAIKRLQQAQLYPIAIFIKPKSIEA LMEMNRRQTYEQANKIYDKA
  MKLEQEFGEYFTAIVQGDSLEEIYN KIKQIIEDQSGHYIWVPSPEKLTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: DLG3 discs large MAGUK scaffold protein 3 [ Homo sapiens (human) ]
• Official Symbol: DLG3
• Synonyms: MRX; XLMR; MRX90; NEDLG; SAP102; XLID90; PPP1R82
• Gene ID: 1741
• mRNA Refseq: NM_021120.4
• Protein Refseq: NP_066943.2
• MIM: 300189
• UniProt ID: Q92796