Recombinant Full Length Human DIS3L Protein, GST-tagged

• Cat.No.: DIS3L-2575HF
• Product Overview: Human DIS3L full-length ORF ( NP_588616.1, 1 a.a. - 971 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The cytoplasmic RNA exosome complex degrades unstable mRNAs and is involved in the regular turnover of other mRNAs. The protein encoded by this gene contains 3'-5' exoribonuclease activity and is a catalytic component of this complex. [provided by RefSeq, May 2016]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 137.5 kDa
• Protein length: 971 amino acids
• AA Sequence: MQTACQAVQHQRGRRQYNKLRNLLK DARHDCILFANEFQQCCYLPRERGE SMEKWQTRSIYNAAVWYYHHCQDRM PIVMVTEDEEAIQQYGSETEGVFVI TFKNYLDNFWPDLKAAHELCDSILQ SRRERENESQESHGKEYPEHLPLEV LEAGIKSGRYIQGILNVNKHRAQIE AFVRLQGASSKDSDLVSDILIHGMK ARNRSIHGDVVVVELLPKNEWKGRT VALCENDCDDKASGESPSEPMPTGR VVGILQKNWRDYVVTFPSKEEVQSQ GKNAQKILVTPWDYRIPKIRISTQQ AETLQDFRVVVRIDSWESTSVYPNG HFVRVLGRIGDLEGEIATILVENSI SVIPFSEAQMCEMPVNTPESPWKVS PEEEQKRKDLRKSHLVFSIDPKGCE DVDDTLSVRTLNNGNLELGVHIADV THFVAPNSYIDIEARTRATTYYLAD RRYDMLPSVLSADLCSLLGGVDRYA VSIMWELDKASYEIKKVWYGRTIIR SAYKLFYEAAQELLDGNLSVVDDIP EFKDLDEKSRQAKLEELVWAIGKLT DIARHVRAKRDGCGALELEGVEVCV QLDDKKNIHDLIPKQPLEVHETVAE CMILANHWVAKKIWESFPHQALLRQ HPPPHQEFFSELRECAKAKGFFIDT RSNKTLADSLDNANDPHDPIVNRLL RSMATQAMSNALYFSTGSCAEEEFH HYGLALDKYTHFTSPIRRYSDIVVH RLLMAAISKDKKMEIKGNLFSNKDL EELCRHINNRNQAAQHSQKQSTELF QCMYFKDKDPATEERCISDGVIYSI RTNGVLLFIPRFGIKGAAYLKNKDG LVISCGPDSCSEWKPGSLQRFQNKI TSTTTDGESVTFHLFDHVTVRISIQ ASRCHSDTIRLEIISNKPYKIPNTE LIHQSSPLLKSELVKEVTKSVEEAQ LAQEVKVNIIQEEYQEYRQTKGRSL YTLLEEIRDLALLDVSNNYGI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DIS3L DIS3 mitotic control homolog (S. cerevisiae)-like [ Homo sapiens ]
• Official Symbol: DIS3L
• Synonyms: DIS3L; DIS3 mitotic control homolog (S. cerevisiae)-like; DIS3-like exonuclease 1; FLJ38088; KIAA1955; MGC4562; DIS3L1
• Gene ID: 115752
• mRNA Refseq: NM_001143688
• Protein Refseq: NP_001137160
• MIM: 614183
• UniProt ID: Q8TF46