Recombinant Full Length Human DGKA Protein

• Cat.No.: DGKA-125HF
• Product Overview: Recombinant full length Human DGKA with N terminal proprietary tag; Predicted MWt 106.96 kDa including the tag.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Protein Length: 735 amino acids
• Description: The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
• Form: Liquid
• Molecular Mass: 106.960kDa inclusive of tags
• AA Sequence: MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMA KYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFET GHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFK LYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPIL QEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTL KDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKY TVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESG RCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAVGHECD CGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNL STSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYI LNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGW ILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQ NLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQI INNYFSIGVDASIAHRFYIMREKYPEKFNSRMKNKLWYFE FATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVL NIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPD ILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLA KCSEITFHTTKTLPMQIDGEPWVQTPCTIKITHKNQMPML MGPPPRSTNFFGFLS
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: DGKA diacylglycerol kinase, alpha 80kDa [ Homo sapiens ]
• Official Symbol: DGKA
• Synonyms: DGKA; diacylglycerol kinase, alpha 80kDa; DAGK, DAGK1, diacylglycerol kinase, alpha (80kD); diacylglycerol kinase alpha; DGK alpha
• Gene ID: 1606
• mRNA Refseq: NM_001345
• Protein Refseq: NP_001336
• MIM: 125855
• UniProt ID: P23743