Recombinant Full Length Human DFNA5 Protein, GST-tagged

• Cat.No.: DFNA5-2482HF
• Product Overview: Human DFNA5 full-length ORF ( NP_004394.1, 1 a.a. - 496 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 81 kDa
• Protein length: 496 amino acids
• AA Sequence: MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DFNA5 deafness, autosomal dominant 5 [ Homo sapiens ]
• Official Symbol: DFNA5
• Synonyms: DFNA5; deafness, autosomal dominant 5; non-syndromic hearing impairment protein 5; ICERE 1; nonsyndromic hearing impairment protein; inversely correlated with estrogen receptor expression 1; ICERE-1
• Gene ID: 1687
• mRNA Refseq: NM_001127453
• Protein Refseq: NP_001120925
• MIM: 608798
• UniProt ID: O60443