Recombinant Full Length Human DDX58 Protein, GST-tagged

• Cat.No.: DDX58-6897HF
• Product Overview: Recombinant Human full-length DDX58 (1 a.a. - 925 a.a.) fused with GST-tag at N-terminal, was expressed in vitro wheat germ expression system.

Specification

• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 133 kDa
• Protein length: 925 amino acids
• Applications: ELISA; WB
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.

Gene Information

• Gene Name: RIGI RNA sensor RIG-I [ Homo sapiens (human) ]
• Official Symbol: DDX58
• Synonyms: DDX58; RIGI; RIG-I; RLR-1; RIG-1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; probable ATP-dependent RNA helicase DDX58; RNA helicase RIG-I; DEAD box protein 58; RIG-I-like receptor 1; retinoic acid inducible gene I; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; EC 3.6.4.13; DKFZp434J1111; FLJ13599
• Gene ID: 23586
• mRNA Refseq: NM_014314
• Protein Refseq: NP_055129
• MIM: 609631
• UniProt ID: O95786