Recombinant Full Length Human CRX Protein

• Cat.No.: CRX-93HF
• Product Overview: Recombinant full length Human CORD2 with a N terminal proprietary tag; Predicted MWt 59.00 kDa.

Specification

• Description: The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 59.000kDa inclusive of tags
• Protein length: 299 amino acids
• AA Sequence: MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQR RERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPE SRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATV SIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASA FCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGP SVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTY NPMDPLDYKDQSAWKFQIL
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: CRX cone-rod homeobox [ Homo sapiens ]
• Official Symbol: CRX
• Synonyms: CRX; cone-rod homeobox; CORD2; cone-rod homeobox protein; CRD; LCA7; orthodenticle homeobox 3; OTX3
• Gene ID: 1406
• mRNA Refseq: NM_000554
• Protein Refseq: NP_000545
• MIM: 602225
• UniProt ID: O43186