Recombinant Full Length Human COL4A6 Protein, GST-tagged

• Cat.No.: COL4A6-2165HF
• Product Overview: Human COL4A6 full-length ORF ( AAH05305, 1 a.a. - 73 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 73 amino acids
• Description: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
• Molecular Mass: 33.77 kDa
• AA Sequence: MLINKLWLLLVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARHNLQLLNDMAGRLYHFSEVLPNLF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COL4A6 collagen, type IV, alpha 6 [ Homo sapiens ]
• Official Symbol: COL4A6
• Synonyms: COL4A6; collagen, type IV, alpha 6; collagen alpha-6(IV) chain; collagen alpha 6 type IV; collagen IV, alpha-6 polypeptide; dJ889N15.4 (Collagen Alpha 6(IV)); collagen of basement membrane, alpha-6; DELXq22.3; CXDELq22.3; MGC88184
• Gene ID: 1288
• mRNA Refseq: NM_001847
• Protein Refseq: NP_001838
• MIM: 303631
• UniProt ID: Q14031