Recombinant Full Length Human CDH20 Protein, N-His-tagged

• Cat.No.: CDH20-22HFL
• Product Overview: Recombinant Full Length Human CDH20 Protein, fused to His-tag at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
• Form: 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol.
• Molecular Mass: 85.1 kDa
• AA Sequence: A DNA sequence encoding human full-length CDH20
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Store at -80 centigrade.
• Concentration: >0.05 μg/μL as determined by microplate BCA method.
• Use/Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: CDH20 cadherin 20 [ Homo sapiens (human) ]
• Official Symbol: CDH20
• Synonyms: CDH20; cadherin 20; Cdh7; CDH7L3
• Gene ID: 28316
• mRNA Refseq: NM_031891.4
• Protein Refseq: NP_114097.2
• MIM: 605807
• UniProt ID: Q9HBT6