CDH20
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Official Full Name
cadherin 20, type 2 -
Overview
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. -
Synonyms
CDH20;cadherin 20, type 2;cadherin-20;Cdh7;CDH7L3;FLJ37047
Recombinant Proteins
- Human
- Rat
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
CDH20 involved in several pathways and played different roles in them. We selected most pathways CDH20 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDH20 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH20 itself. We selected most functions CDH20 had, and list some proteins which have the same functions with CDH20. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | SYT5A,FREM2,LDLRB,PADI4,CETN3,CCDC102A,EFHD1,SLIT1B,MYLPFB,FSTL1A |
Interacting Protein
CDH20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH20 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH20.
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References
- Jeuck, TLA; Wittekind, C; et al. Gastric carcinoma: stage migration by immunohistochemically detected lymph node micrometastases. GASTRIC CANCER 18:100-108(2015).
- Bodnar, M; Szylberg, L; et al. Immunohistochemical expression of p27(kip1) in metastatic laryngeal squamous cell carcinoma. ADVANCES IN MEDICAL SCIENCES 59:206-212(2014).
