Recombinant Full Length Human CAPG Protein, GST-tagged

• Cat.No.: CAPG-2813HF
• Product Overview: Human CAPG full-length ORF (AAH00728.1, 1 a.a. - 348 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 63.8 kDa
• Protein length: 348 amino acids
• AA Sequence: MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPIFKQFFKDWK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CAPG capping protein (actin filament), gelsolin-like [ Homo sapiens ]
• Official Symbol: CAPG
• Synonyms: CAPG; capping protein (actin filament), gelsolin-like; AFCP; macrophage-capping protein; macrophage capping protein; MCP; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein CAP-G
• Gene ID: 822
• mRNA Refseq: NM_001256139
• Protein Refseq: NP_001243068
• MIM: 153615
• UniProt ID: P40121