Recombinant Full Length Human BEST1 Protein, GST-tagged
Cat.No. : | BEST1-1573HF |
Product Overview : | Human BEST1 full-length ORF ( AAH41664.1, 1 a.a. - 604 a.a.) recombinant protein with GST-tag at N-terminal. |
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Species : | Human |
Source : | In Vitro Cell Free System |
Tag : | GST |
Protein Length : | 604 amino acids |
Description : | This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms |
Form : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 95.5 kDa |
AA Sequence : | MFEKLTLYCD SYIQLIPISF VLGFYVTLVV TRWWNQYENL PWPDRLMSLV SGFVEGKDEQ GRLLRRTLIR YANLGNVLIL RSVSTAVYKR FPSAQHLVQA GFMTPAEHKQ LEKLSLPHNM FWVPWVWFAN LSMKAWLGGR IRDPILLQSL LNEMNTLRTQ CGHLYAYDWI SIPLVYTQVV TVAVYSFFLT CLVGRQFLNP AKAYPGHELD LVVPVFTFLQ FFFYVGWLKV AEQLINPFGE DDDDFETNWI VDRNLQVSLL AVDEMHQDLP RMEPDMYWNK PEPQPPYTAA SAQFRRVSFM GSTFNISLNK EEMEFQPNQE DEEDAHAGII GRFLGLQSHD HHPPRANSRT KLLWPKRESL LHEGLPKNHK AAKQNVRGQE DNKAWKLKAV DAFKSAPLYQ RPGYYSAPQT PLSPTPMFFP LEPSAPSKLH SVTGIDTKDK SLKTVSSGAK KSFELLSESD GALMEHPEVS QVRRKTVEFN LTDMPEIPEN HLKEPLEQSP TNIHTTLKDH MDPYWALENR SVLHLNQGHC IALCPTPASL ALSLPFLHNF LGFHHCQSTL DLRPALAWGI YLATFTGILG KCSGPFLTSP WYHPEDFLGP GEGR |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name | BEST1 bestrophin 1 [ Homo sapiens ] |
Official Symbol | BEST1 |
Synonyms | BEST1; bestrophin 1; vitelliform macular dystrophy 2 , VMD2; bestrophin-1; BEST; Best disease; BMD; vitelliform macular dystrophy protein 2; ARB; RP50; VMD2; TU15B |
Gene ID | 7439 |
mRNA Refseq | NM_001139443 |
Protein Refseq | NP_001132915 |
MIM | 607854 |
UniProt ID | O76090 |
◆ Recombinant Proteins | ||
BEST1-503H | Recombinant Human bestrophin 1, His-tagged | +Inquiry |
BEST1-1857HFL | Recombinant Full Length Human BEST1 Protein, C-Flag-tagged | +Inquiry |
RFL18265MF | Recombinant Full Length Mouse Bestrophin-1(Best1) Protein, His-Tagged | +Inquiry |
RFL30674MF | Recombinant Full Length Macaca Fascicularis Bestrophin-1(Best1) Protein, His-Tagged | +Inquiry |
BEST1-1573HF | Recombinant Full Length Human BEST1 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
BEST1-1910HCL | Recombinant Human BEST1 cell lysate | +Inquiry |
Not For Human Consumption!
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