Recombinant Full Length Human BCL3 Protein, GST-tagged

• Cat.No.: BCL3-1606HF
• Product Overview: Human BCL3 full-length ORF ( NP_005169.1, 1 a.a. - 446 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: In Vitro Cell Free System
• Tag: GST
• Protein Length: 446 amino acids
• Description: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq
• Form: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 73.2 kDa
• AA Sequence: MDEGPVDLRT RPKAAGLPGA ALPLRKRPLR APSPEPAAPR GAAGLVVPLD PLRGGCDLPA VPGPPHGLAR PEALYYPGAL LPLYPTRAMG SPFPLVNLPT PLYPMMCPME HPLSADIAMA TRADEDGDTP LHIAVVQGNL PAVHRLVNLF QQGGRELDIY NNLRQTPLHL AVITTLPSVV RLLVTAGASP MALDRHGQTA AHLACEHRSP TCLRALLDSA APGTLDLEAR NYDGLTALHV AVNTECQETV QLLLERGADI DAVDIKSGRS PLIHAVENNS LSMVQLLLQH GANVNAQMYS GSSALHSASG RGLLPLVRTL VRSGADSSLK NCHNDTPLMV ARSRRVIDIL RGKATRPAST SQPDPSPDRS ANTSPESSSR LSSNGLLSAS PSSSPSQSPP RDPPGFPMAP PNFFLPSPSP PAFLPFAGVL RGPGRPVPPS PAPGGS
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BCL3 B-cell CLL/lymphoma 3 [ Homo sapiens ]
• Official Symbol: BCL3
• Synonyms: BCL3; B-cell CLL/lymphoma 3; BCL4, D19S37; B-cell lymphoma 3 protein; B cell leukemia/lymphoma 3; B cell lymphoma 3 encoded protein; chronic lymphatic leukemia protein; BCL-3; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; BCL4; D19S37
• Gene ID: 602
• mRNA Refseq: NM_005178
• Protein Refseq: NP_005169
• MIM: 109560
• UniProt ID: P20749