BCL3
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Official Full Name
B-cell CLL/lymphoma 3 -
Overview
The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. -
Synonyms
BCL4;D19S37;BCL3;B-cell lymphoma 3 protein;BCL-3;OTTHUMP00000200151;OTTHUMP00000200152;proto-oncogene BCL3;B-cell leukemia/lymphoma 3;B-cell lymphoma 3-encoded protein;chronic lymphatic leukemia protein
Recombinant Proteins
- Human
- Mouse
- Rat
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- His&T7
- Non
- DDK&Myc
- Avi&Fc&His
Involved Pathway
BCL3 involved in several pathways and played different roles in them. We selected most pathways BCL3 participated on our site, such as TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TNF signaling pathway | CASP8,PIK3R5,CXCL2,PIK3CG,TRAF5,CREB3L1,MAPK10,IKBKB,ITCH,PIK3CA |
Protein Function
BCL3 has several biochemical functions, for example, DNA binding,protein binding,protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL3 itself. We selected most functions BCL3 had, and list some proteins which have the same functions with BCL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding, bridging | NEFL,NEFH,FSCN1A,RAD50,AMFR,PPP4R2,SPRR1B,FSCN2B,CRADD,FRMD4A |
| DNA binding | HIST1H4G,FLI1,MYEF2,PPARGC1A,HIST1H2AA,ZFML,HOXA13,ZNF692,RUNX1T1,TSN |
| transcription factor binding | WWP2,NAB1,ZFPM1,ADD1,RNF19A,MYBBP1A,YWHAZ,NCOA2,PDX1,CD34 |
| transcription factor activity, sequence-specific DNA binding | NFIL3-3,NFE2L2,ZFP641,NKX6-1,DMRTC2,GATA2,ZNF92,ZNF8,GABPA,TRP53 |
| protein binding | SELS,GRB7,TMEM19,GRHL2,PTPRJ,RHOG,KLHL41,PRPSAP1,LOR,ADNP |
Interacting Protein
BCL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL3.
LCK;BCL10;CTBP2;PIR;FYN;ANKRD28;NFKB1;NFKB2;RELB;RELA;REL
Resources
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References
- Komai, K; Niwa, Y; et al. Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. FEBS LETTERS 589:738-743(2015).
- Chen, H; Zhang, Q; et al. Patterning of light-extraction nanostructures on sapphire substrates using nanoimprint and ICP etching with different masking materials. NANOTECHNOLOGY 26:-(2015).
