Recombinant Full Length Human BCL2L10 Protein, GST-tagged

Cat.No. : BCL2L10-1594HF
Product Overview : Human BCL2L10 full-length ORF ( NP_065129.1, 1 a.a. - 204 a.a.) recombinant protein with GST-tag at N-terminal.
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Species : Human
Source : In Vitro Cell Free System
Tag : GST
Protein Length : 204 amino acids
Description : The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq
Form : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 49.6 kDa
AA Sequence : MVDQLRERTT MADPLRERTE LLLADYLGYC AREPGTPEPA PSTPEAAVLR SAAARLRQIH RSFFSAYLGY PGNRFELVAL MADSVLSDSP GPTWGRVVTL VTFAGTLLER GPLVTARWKK WGFQPRLKEQ EGDVARDCQR LVALLSSRLM GQHRAWLQAQ GGWDGFCHFF RTPFPLAFWR KQLVQAFLSC LLTTAFIYLW TRLL
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name BCL2L10 BCL2-like 10 (apoptosis facilitator) [ Homo sapiens ]
Official Symbol BCL2L10
Synonyms BCL2L10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCL B; Boo; Diva; bcl2-L-10; apoptosis regulator Bcl-B; anti-apoptotic protein NrH; BCL-B; MGC129810; MGC129811
Gene ID 10017
mRNA Refseq NM_020396
Protein Refseq NP_065129
MIM 606910
UniProt ID Q9HD36

Not For Human Consumption!

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