Recombinant Full Length Human B4GALT2 Protein, GST-tagged

Description :	This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Two transcript variants encoding the same protein have been found for this gene.
Source :	In Vitro Cell Free System
Species :	Human
Tag :	GST
Form :	50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass :	59.40 kDa
Protein length :	306 amino acids
AA Sequence :	MPSTQLLAAA AAAATAPGPT PPPLAPGSLR SPVPCPVPRL PRCHPVLTRH LVLRVHRENP GVLMGGRYTP PDCTPAQTVA VIIPFRHREH HLRYWLHYLH PILRRQRLRY GVYVINQHGE DTFNRAKLLN VGFLEALKED AAYDCFIFSD VDLVPMDDRN LYRCGDQPRH FAIAMDKFGF RLPYAGYFGG VSGLSKAQFL RINGFPNEYW GWGGEDDDIF NRISLTGMKV SRPDIRIGRY RMIKHDRDKH NEPNPQRFTK IQNTKLTMKR DGIGSVRYQV LEVSRQPLFT NITVDIGRPP SWPPRG
Storage :	Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Name	B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 [ Homo sapiens ]
Official Symbol	B4GALT2
Synonyms	B4GALT2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2; beta-1,4-galactosyltransferase 2; beta4Gal T2; beta-4-GalT2; beta-1,4-GalTase 2; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2; B4Gal-T2; B4Gal-T3; beta4Gal-T2
Gene ID	8704
mRNA Refseq	NM_001005417
Protein Refseq	NP_001005417
MIM	604013
UniProt ID	O60909