Recombinant Full Length Human ASB7 Protein, GST-tagged

• Cat.No.: ASB7-1361HF
• Product Overview: Human ASB7 full-length ORF ( NP_078984.2, 1 a.a. - 274 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 57.1 kDa
• Protein length: 274 amino acids
• AA Sequence: MLHHHCRRNP ELQEELQIQA AVAAGDVHTV RKMLEQGYSP NGRDANGWTL LHFSAARGKE RCVRVFLEHG ADPTVKDLIG GFTALHYAAM HGRARIARLM LESEYRSDII NAKSNDGWTP LHVAAHYGRD SFVRLLLEFK AEVDPLSDKG TTPLQLAIIR ERSSCVKILL DHNANIDIQN GFLLRYAVIK SNHSYCRMFL QRGADTNLGR LEDGQTPLHL SALRDDVLCA RMLYNYGADT NTRNYEGQTP LAVSISISGS SRPCLDFLQE VTSM
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASB7 ankyrin repeat and SOCS box containing 7 [ Homo sapiens ]
• Official Symbol: ASB7
• Synonyms: ASB7; ankyrin repeat and SOCS box containing 7; ankyrin repeat and SOCS box protein 7; ASB-7; ankyrin repeat and SOCS box-containing 7; FLJ22551; FLJ25192
• Gene ID: 140460
• mRNA Refseq: NM_024708
• Protein Refseq: NP_078984
• MIM: 615052
• UniProt ID: Q9H672