Recombinant Full Length Human APOBEC3B Protein, GST-tagged

• Cat.No.: APOBEC3B-1143HF
• Product Overview: Human APOBEC3B full-length ORF ( AAH53859.1, 1 a.a. - 251 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 56.2 kDa
• Protein length: 251 amino acids
• AA Sequence: MNPQIRNPME RMYRDTFYDN FENEPILYGR SYTWLCYEVK IKRGRSNLLW DTGVFRGQVY FEPQYHAEMC FLSWFCGNQL PAYKCFQITW FVSWTPCPDC VAKLAEFLSE HPNVTLTISA ARLYYYWERD YRRALCRLSQ AGARVKIMDY EEFAYCWENF VYNEGQQFMP WYKFDENYAF LHRTLKEILR LRIFSVAFTA AMRSCASWTW FLLCSWTRPR STGSLGSSPG APASPGAVPG KCVRSFRRTH T
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B [ Homo sapiens ]
• Official Symbol: APOBEC3B
• Synonyms: APOBEC3B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; probable DNA dC->dU-editing enzyme APOBEC-3B; FLJ21201; phorbolin 3; PHRBNL; probable DNA dC-> dU-editing enzyme APOBEC-3B; phorbolin 2; phorbolin-2/3; cytidine deaminase; phorbolin-1-related protein; ARP4; ARCD3; APOBEC1L; bK150C2.2; DJ742C19.2
• Gene ID: 9582
• mRNA Refseq: NM_004900
• Protein Refseq: NP_004891
• MIM: 607110
• UniProt ID: Q9UH17