Recombinant Full Length Human ALS2CR11 Protein, GST-tagged

• Cat.No.: ALS2CR11-1490HF
• Product Overview: Human ALS2CR11 full-length ORF ( AAH30659.1, 1 a.a. - 623 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes this gene. The encoded protein contains a calcium-dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction. [provided by RefSeq, Jun 2016]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 97.5 kDa
• Protein length: 623 amino acids
• AA Sequence: MEPPQETNRP FSTLDNRSGQ VQVLSATPLL QRNPYSSPDI MHIKGSEASS VPYALNQGTT ALPKNKNQEG TGHRLLNMLR KTLKESDSEE LEITQETPNL VPFGDVVGCL GIHIKNCRHF MPKISLQHYA NLFIRISINK AVKCTKMCSL LSKNDEKNTV IKFDEVKYFS VQVPRRYDDK RNNILLELIQ YDNREKRAFL LGSVQIHLYE VIQKGCFIEE VQVLHGNIFV CRLEVEFMFS YGNFGYGFSH QLKPLQKITE PSMFMNLAPP PERTDPVTKV ITPQTVEYPA FLSPDLNVTV GTPAVQSSNQ PSVVRLEKLQ QQPRERLEKM KKEYRNLNTW IDKANYLESI LMPKLEHKDS EETNIDEASE NTKSNQPEEE LENIVGVDIP LVNEEAETTA NELLDNDSEK GLTIPTLNQS DQDNSTADAS KNDESTPSPT EVHSLCTISN QETIKAGRIP PLGERQSESM PDRKMKNVFF PLEVKLKDNY PSILKADSSL SEVAFSPKEY NSPSFRPEYI EFKPKFQDCS DKFEDLHDMT SFTHLKKVKS RSRLLGKSSD DIHNHARHSA RPYTAPEVNK QRESYSGKFT SRRMVSSGLV HINDKTSDYE MHKMRPKKIK RGY
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 [ Homo sapiens ]
• Official Symbol: ALS2CR11
• Synonyms: ALS2CR11; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein; FLJ25351; FLJ40332; DKFZp686H0636
• Gene ID: 151254
• mRNA Refseq: NM_001168216
• Protein Refseq: NP_001161688
• MIM: 619776
• UniProt ID: Q53TS8