Recombinant Full Length Human ALDH8A1 Protein, GST-tagged

• Cat.No.: ALDH8A1-1417HF
• Product Overview: Human ALDH8A1 full-length ORF ( NP_072090.1, 1 a.a. - 487 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 79.8 kDa
• Protein length: 487 amino acids
• AA Sequence: MAGTNALLML ENFIDGKFLP CSSYIDSYDP STGEVYCRVP NSGKDEIEAA VKAAREAFPS WSSRSPQERS RVLNQVADLL EQSLEEFAQA ESKDQGKTLA LARTMDIPRS VQNFRFFASS SLHHTSECTQ MDHLGCMHYT VRAPVGVAGL ISPWNLPLYL LTWKIAPAMA AGNTVIAKPS ELTSVTAWML CKLLDKAGVP PGVVNIVFGT GPRVGEALVS HPEVPLISFT GSQPTAERIT QLSAPHCKKL SLELGGKNPA IIFEDANLDE CIPATVRSSF ANQGEICLCT SRIFVQKSIY SEFLKRFVEA TRKWKVGIPS DPLVSIGALI SKAHLEKVRS YVKRALAEGA QIWCGEGVDK LSLPARNQAG YFMLPTVITD IKDESCCMTE EIFGPVTCVV PFDSEEEVIE RANNVKYGLA ATVWSSNVGR VHRVAKKLQS GLVWTNCWLI RELNLPFGGM KSSGIGREGA KDSYDFFTEI KTITVKH
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALDH8A1 aldehyde dehydrogenase 8 family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH8A1
• Synonyms: ALDH8A1; aldehyde dehydrogenase 8 family, member A1; aldehyde dehydrogenase family 8 member A1; ALDH12; aldehyde dehydrogenase 12; aldehyde dehydrogenase family protein; DJ352A20.2; MGC138650; DKFZp779D2315
• Gene ID: 64577
• mRNA Refseq: NM_001193480
• Protein Refseq: NP_001180409
• MIM: 606467
• UniProt ID: Q9H2A2