Recombinant Full Length Human ADH1B Protein, GST-tagged

• Cat.No.: ADH1B-924HF
• Product Overview: Human ADH1B full-length ORF ( AAH33009.1, 1 a.a. - 375 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 66.99 kDa
• Protein length: 375 amino acids
• AA Sequence: MSTAGKVIKC KAAVLWEVKK PFSIEDVEVA PPKAYEVRIK MVAVGICRTD DHVVSGNLVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK CRVCKNPESN YCLKNDLGNP RGTLQDGTRR FTCRGKPIHH FLGTSTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAVM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPASQ NLSINPMLLL TGRTWKGAVY GGFKSKEGIP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TVLTF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide [ Homo sapiens ]
• Official Symbol: ADH1B
• Synonyms: ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide; ADH2; alcohol dehydrogenase 1B; ADH, beta subunit; aldehyde reductase; alcohol dehydrogenase subunit beta; alcohol dehydrogenase 2 (class I), beta polypeptide
• Gene ID: 125
• mRNA Refseq: NM_000668
• Protein Refseq: NP_000659
• MIM: 103720
• UniProt ID: P00325