Recombinant Full Length Human ACSL6 Protein, GST-tagged

• Cat.No.: ACSL6-805HF
• Product Overview: Human ACSL6 full-length ORF ( AAH47453, 1 a.a. - 622 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 94.16 kDa
• Protein length: 622 amino acids
• AA Sequence: MQTQEILRIL RLPELGDLGQ FFRSLSATTL DSGGARRSVI GSGPQLLTHY YDDARTMYQV FRRGLSISGN GPCLGFRKPK QPYQWLSYQE VADRAEFLGS GLLQHNCKAC TDQFIGVFAQ NRPEWIIVEL ACYTYSMVVV PLYDTLGPGA IRYIINTADI STVIVDKPQK AVLLLEHVER KETPGLKLII LMDPFEEALK ERGQKCGVVI KSMQAVEDCG QANHQAPVPP QPDDLSIVCF TSGTTGNPKG AMLTHGNVVA DFSGFLKVTE GDIRLLSDDM KALCPTIFPV VPRLLNRMYD KIFSQANTPL KRWLLEFAAK RKQAEVRSGI IRNDSIWDEL FFNKIQASLG GCVRMIVTGA APASPTVLGF LRAALGCQVY EGYGQTECTA GCTFTTPGDW TSGHVGAPLP CNHIKLVDVE ELNYWACKGE GEICVRGPNV FKGYLKDPDR TKEALDSDGW LHTGDIGKWL PAGTLKIIDR KKHIFKLAQG EYVAPEKIEN IYIRSQPVAQ IYVHGDSLKA FLVGIVVPDP EVMPSWAQKR GIEGTYADLC TNKDLKKAIL EDMVRLGKES GLHSFEQVKA IHIHSDMFSV QNGLLTPTLK AKRPELREYF KKQIEELYSI SM
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACSL6 acyl-CoA synthetase long-chain family member 6 [ Homo sapiens ]
• Official Symbol: ACSL6
• Synonyms: ACSL6; acyl-CoA synthetase long-chain family member 6; FACL6, fatty acid Coenzyme A ligase, long chain 6; long-chain-fatty-acid--CoA ligase 6; ACS2; KIAA0837; LACS2; LACS5; long fatty acyl-CoA synthetase 2; fatty-acid-Coenzyme A ligase, long-chain 6; FACL6; LACS 6; FLJ16173
• Gene ID: 23305
• mRNA Refseq: NM_001009185
• Protein Refseq: NP_001009185
• MIM: 604443
• UniProt ID: Q9UKU0