ACSL6
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Official Full Name
acyl-CoA synthetase long-chain family member 6 -
Overview
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ACSL6;acyl-CoA synthetase long-chain family member 6;FACL6, fatty acid Coenzyme A ligase, long chain 6;long-chain-fatty-acid--CoA ligase 6;ACS2;KIAA0837;LACS2;LACS5;long fatty acyl-CoA synthetase 2;fatty-acid-Coenzyme A ligase, long-chain 6;FAC
Recombinant Proteins
- Human
- Rat
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- E.coli
- In Vitro Cell Free System
- E. coli
- E.coli expression system
- GST
- His
- Myc&DDK
- His&Fc&Avi
- N-GST
Involved Pathway
ACSL6 involved in several pathways and played different roles in them. We selected most pathways ACSL6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSL6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ACSL6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ACSL6 itself. We selected most functions ACSL6 had, and list some proteins which have the same functions with ACSL6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ACSL6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSL6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSL6.
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References
- Saatchi, M; Beever, JE; et al. QTLs associated with dry matter intake, metabolic mid-test weight, growth and feed efficiency have little overlap across 4 beef cattle studies. BMC GENOMICS 15:-(2014).
- Wang, S; Matthan, NR; et al. Lipid content in hepatic and gonadal adipose tissue parallel aortic cholesterol accumulation in Mice fed diets with different omega-6 PUFA to EPA plus DHA ratios. CLINICAL NUTRITION 33:260-266(2014).
