Recombinant Full Length Human ACSL5 Protein, GST-tagged

• Cat.No.: ACSL5-804HF
• Product Overview: Human ACSL5 full-length ORF ( NP_057318.2, 1 a.a. - 739 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 108.7 kDa
• Protein length: 739 amino acids
• AA Sequence: MDALKPPCLW RNHERGKKDR DSCGRKNSEP GSPHSLEALR DAAPSQGLNF LLLFTKMLFI FNFLFSPLPT PALICILTFG AAIFLWLITR PQPVLPLLDL NNQSVGIEGG ARKGVSQKNN DLTSCCFSDA KTMYEVFQRG LAVSDNGPCL GYRKPNQPYR WLSYKQVSDR AEYLGSCLLH KGYKSSPDQF VGIFAQNRPE WIISELACYT YSMVAVPLYD TLGPEAIVHI VNKADIAMVI CDTPQKALVL IGNVEKGFTP SLKVIILMDP FDDDLKQRGE KSGIEILSLY DAENLGKEHF RKPVPPSPED LSVICFTSGT TGDPKGAMIT HQNIVSNAAA FLKCVEHAYE PTPDDVAISY LPLAHMFERI VQAVVYSCGA RVGFFQGDIR LLADDMKTLK PTLFPAVPRL LNRIYDKVQN EAKTPLKKFL LKLAVSSKFK ELQKGIIRHD SFWDKLIFAK IQDSLGGRVR VIVTGAAPMS TSVMTFFRAA MGCQVYEAYG QTECTGGCTF TLPGDWTSGH VGVPLACNYV KLEDVADMNY FTVNNEGEVC IKGTNVFKGY LKDPEKTQEA LDSDGWLHTG DIGRWLPNGT LKIIDRKKNI FKLAQGEYIA PEKIENIYNR SQPVLQIFVH GESLRSSLVG VVVPDTDVLP SFAAKLGVKG SFEELCQNQV VREAILEDLQ KIGKESGLKT FEQVKAIFLH PEPFSIENGL LTPTLKAKRG ELSKYFRTQI DSLYEHIQD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACSL5 acyl-CoA synthetase long-chain family member 5 [ Homo sapiens ]
• Official Symbol: ACSL5
• Synonyms: ACSL5; acyl-CoA synthetase long-chain family member 5; FACL5, fatty acid Coenzyme A ligase, long chain 5; long-chain-fatty-acid--CoA ligase 5; ACS2; ACS5; FACL5 for fatty acid coenzyme A ligase 5; fatty acid Coenzyme A ligase; long chain 5; long chain acyl CoA synthetase 5; long chain fatty acid coenzyme A ligase 5; LACS 5; fatty acid coenzyme A ligase 5; long-chain acyl-CoA synthetase 5; long-chain fatty acid coenzyme A ligase 5; fatty-acid-Coenzyme A ligase, long-chain 5; FACL5
• Gene ID: 51703
• mRNA Refseq: NM_016234
• Protein Refseq: NP_057318
• MIM: 605677
• UniProt ID: Q9ULC5