Recombinant Dog Plasminogen Activator, Urokinase

• Cat.No.: PLAU-701D
• Product Overview: Recombinant Dog Plasminogen Activator, Urokinase is expressed inInsect cell culture. MW= 50,000 Da.

Specification

• Species: Dog
• Source: Insect Cells
• Tag: Non
• Description: This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer disease and also with decreased affinity for fibrin-binding. The protein encoded by this gene converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. This gene"s proprotein is cleaved at a Lys-Ile bond by plasmin to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain.
• Form: Frozen liquid.
• Buffer: 0.05M Sodium Acetate; 0.1M NaCl; 1mM EDTA; pH 5.0.
• Concentration: 4.0 mg/ml.
• Aliquot: 1 x 0.1 mg.
• Shipping Conditions: Dry ice.
• Storage: Store at -70°C.

Gene Information

• Gene Name: PLAU plasminogen activator, urokinase [ Canis lupus familiaris ]
• Synonyms: PLAU; plasminogen activator, urokinase; plasminogen activator, urokinase; urokinase-type plasminogen activator
• Gene ID: 403426
• mRNA Refseq: XM_536394
• Protein Refseq: XP_536394
• Chromosome Location: 4
• Pathway: Complement and coagulation cascades