Recombinant Cynomolgus MUSK Protein, His-tagged

• Cat.No.: MUSK-50C
• Product Overview: Recombinant Cynomolgus Monkey MUSK Protein (Leu24-Thr495) with a C-terminal 6-His tag was expressed in Chinese Hamster Ovary cell line.

Specification

• Species: Cynomolgus
• Source: CHO
• Tag: His
• Protein Length: 24-495aa
• Description: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
• Tag: C-6×His
• Bio-activity: Measured by its binding ability in a functional ELISA. In the presence of Recombinant Human Agrin, immobilized Recombinant Cynomolgus Monkey MuSK His-tag at 2 μg/mL (100 μL/well), Recombinant Human LRP-4 binds with an ED50 of 25.0-200 ng/mL.
• Molecular Mass: 53 kDa
• Endotoxin: < 0.1 EU/μg by LAL.
• Purity: > 95 %, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• N-terminal Sequence Analysis: Leu24
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Shipping: The product is shipped at ambient temperature.
• Reconstitution: Reconstitute at 500 μg/mL in PBS.

Gene Information

• Gene Name: MUSK muscle associated receptor tyrosine kinase [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: MUSK
• Synonyms: MUSK; muscle associated receptor tyrosine kinase; muscle, skeletal receptor tyrosine-protein kinase
• Gene ID: 102127677
• mRNA Refseq: XM_005581093
• Protein Refseq: XP_005581150
• UniProt ID: G7PRP5