Recombinant Human Muscle, Skeletal, Receptor Tyrosine Kinase, GST-tagged

• Cat.No.: MUSK-5457H
• Product Overview: Recombinant humanMUSK catalytic domain (amino acids 519-869), GST-tagged.

Specification

• Cat. No.: MUSK-5457H
• Description: MUSK plays an important and selective rolein many aspects of skeletal muscle development and function through theinitial step of postsynaptic differentiation and formation of end-plate bandsin cooperation with Rapsyn. No special measures were taken to activate thiskinase.
• Source: Insect cells
• Species: Human
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
• Molecular Weight: 69.4 kDa
• storage: Stablefor 6 months in working aliquots at -80°C. Avoidrepeated freeze-thaw cycles.
• OfficialSymbol: MUSK
• Protein length: 519-869 a.a.

Gene Information

• Gene Name: MUSK muscle, skeletal, receptortyrosine kinase [ Homo sapiens ]
• Synonyms: MUSK; muscle, skeletal,receptor tyrosine kinase; MGC126323; MGC126324; skeletal muscle receptortyrosine kinase; EC 2.7.10.1; Muscle-specific kinase receptor;Muscle-specific tyrosine protein kinase receptor; protein-tyrosine kinase;receptor tyrosine kinase; Muscle, skeletal receptor tyrosine protein kinase
• Gene ID: 4593
• mRNA Refseq: NM_001166280
• Protein Refseq: NP_001159752
• MIM: 601296
• UniProt ID: O15146
• Chromosome Location: 9q31.3-q32
• Function: ATP binding; nucleotidebinding; protein binding; receptor activity; transferase activity;transmembrane receptor protein tyrosine kinase activity