Recombinant Cynomolgus MSLN Protein, Fc tagged

• Cat.No.: MSLN-25C
• Product Overview: Recombinant Cynomolgus MSLN Protein with Fc-tag was expressed in Human cells.

Specification

• Species: Cynomolgus
• Source: Human Cells
• Tag: Fc
• Description: This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
• AA Sequence: DVERTTCPPEKEVHEIDESLIFYKKRELEACVDAALLAAQMDRVDAIPFTYEQLDVLKHKLDELYPQGYPESVIRHLGHLFLKMSPEDIRKWNVTSLETLKALLKVSKGHEMSAQVATLIDRVVVGRGQLDKDTADTLTAFCPGCLCSLSPERLSSVPPSIIGAVRPQDLDTCGPRQLDVLYPKARLAFQNMSGSEYFVKIRPFLGGAPTEDLKALSQQNVSMDLATFMKLRREAVLPLSVAEVQKLLGPHVEGLKVEEQHSPVRDWILKQRQDDLDTLGLGLQGGIPNGYLILDLSVREALSGTPCLLGPGP
• Endotoxin: < 1.0 EU/μg of the protein by the LAL method.
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1.0 mg/mL as determined by BCA method
• Storage Buffer: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4)

Gene Information

• Gene Name: MSLN mesothelin [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: MSLN
• Synonyms: MSLN; mesothelin
• Gene ID: 102130460
• mRNA Refseq: XM_045382794
• Protein Refseq: XP_045238729